Basics of Biochemistry, Molecular Biology, Biophysics:
General Biology: Taxonomy of plants and animals; pro-and eukaryotic organisms; cell organelles and their function; multicellular organization; general physiology; energy transformations; internal transport systems of plants and animals; photosynthesis; respiration; regulation of body fluids and excretory mechanisms; reproductive biology; plant and animal hormones and their action; nervous systems; animal behavior; plant and animal diseases; Mendelian genetics and heredity; basics of developmental biology; biology of populations and communities; evolution; basic principles of ecology; genesis and diversity of organisms.
Buffers; trace elements in biological systems; enzymes and proteins; vitamins; biological oxidations, photosynthesis;carbohydrates and lipids and their metabolism; digestion and absorption; detoxifying mechanisms; nucleic acids;nucleic acid metabolism;nature of gene and its function; genetic code; synthesis of nucleic acids and proteins; regulation of gene expression; operons.
Structure of biomolecules; intra and intermolecular forces; thermodynamics and kinetics of biological systems; enzyme mechanisms and kinetics;principles of X-ray diffraction; IR- and UV- spectroscopy; analytical and biochemical techniques
Microbiology, Cell Biology and Immunology: Classification of microorganisms and their characterization; nutrient requirement for growth; laboratory techniques in microbiology; pathogenic microorganisms and disease; applied microbiology; viruses and fungi; microbial genetics;cell theory; cell architecture; cell division; types of chromosome structure; biochemical genetics- inborn errors of metabolisms; innate and adaptive immunity, antigen antibodies; principles of processes of development.
Mathematical Sciences: Mathematical functions (algebraic, exponential, trigonometric) and their derivatives (derivatives and integrals of simple functions); permutations and combinations; basic probability and volumetric calculations.
The Biotechnology (BT) test paper comprises of Biology, Chemistry, Mathematics and Physics.
BIOLOGY (10+2+3 level)
General Biology: Taxonomy; Heredity; Genetic variation; Conservation; Principles of ecology; Evolution; Techniques in modern biology.
Biochemistry and Physiology: Carbohydrates; Proteins; Lipids; Nucleic acids; Enzymes; Vitamins; Hormones; Metabolism – Glycolysis, TCA cycle, Oxidative Phosphoryation; Photosynthesis. Nitrogen Fixation, Fertilization and Osmoregulation; Vertebrates-Nervous system; Endocrine system; Vascular system; Immune system; Digestive system and Reproductive System.
Basic Biotechnology: Tissue culture; Application of enzymes; Antigen-antibody interaction; Antibody production; Diagnostic aids.
Molecular Biology: DNA; RNA; Replication; Transcription; Translation; Proteins; Lipids and Membranes; Operon model; Gene transfer.
Cell Biology: Cell cycle; Cytoskeletal elements; Mitochondria; Endoplasmic reticulum; Chloroplast; Golgi apparatus; Signaling.
Microbiology: Isolation; Cultivation; Structural features of virus; Bacteria; Fungi; Protozoa; Pathogenic micro-organizms.
Atomic Structure: Bohr’s theory and Schrodinger wave equation; Periodicity in properties; Chemical bonding; Properties of s, p, d and f block elements; Complex formation; Coordination compounds; Chemical equilibria; Chemical thermodynamics (first and second law); Chemical kinetics (zero, first, second and third order reactions); Photochemistry; Electrochemistry; Acid-base concepts; Stereochemistry of carbon compounds; Inductive, electromeric, conjugative effects and resonance; Chemistry of Functional Groups: Hydrocarbons, alkyl halides, alcohols, aldehydes, ketones, carboxylic acids, amines and their derivatives; Aromatic hydrocarbons, halides, nitro and amino compounds, phenols, diazonium salts, carboxylic and sulphonic acids; Mechanism of organic reactions; Soaps and detergents; Synthetic polymers; Biomolecules – amino acids, proteins, nucleic acids, lipids and carbohydrates (polysaccharides); Instrumental techniques – chromatography (TLC, HPLC), electrophoresis, UV-Vis, IR and NMR spectroscopy, mass spectrometry.
Sets, Relations and Functions, Mathematical Induction, Logarithms, Complex numbers, Linear and Quadratic equations, Sequences and Series, Trigonometry, Cartesian System of Rectangular Coordinates, Straight lines and Family, Circles, Conic Sections, Permutations and Combinations, Binomial Theorem, Exponential and Logarithmic Series, Mathematical Logic, Statistics, Three Dimensional Geometry, Vectors, Matrices and Determinants, Boolean Algebra, Probability, Functions, limits and Continuity, Differentiation, Application of Derivatives, Definite and Indefinite Integrals, Differential Equations.
Physical World and Measurement, Elementary Statics and Dynamics, Kinematics, Laws of Motion, Work, Energy and Power, Electrostatics, Current electricity, Magnetic Effects of Current and Magnetism, Electromagnetic Induction and Alternating Current, Electromagnetic waves, Optics, Dual Nature of Matter and Radiations, Atomic Nucleus, Solids and Semiconductor Devices, Principles of Communication, Motion of System of Particles and Rigid Body, Gravitation, Mechanics of Solids and Fluids, Heat and Thermodynamics, Oscillations, Waves.
The Mathematical Statistics (MS) test paper comprises of Mathematics (40% weightage) and Statistics (60%weightage).
Mathematical Methods: Calculus of single and multiple variables, partial derivatives, Jacobian, imperfect and perfect differentials, Taylor expansion, Fourier series. Vector algebra, Vector Calculus, Multiple integrals, Divergence theorem, Green’s theorem, Stokes’ theorem. First order equations and linear second order differential equations with constant coefficients. Matrices and determinants, Algebra of complex numbers.
Mechanics and General Properties of Matter: Newton’s laws of motion and applications, Velocity and acceleration in Cartesian, polar and cylindrical coordinate systems, uniformly rotating frame, centrifugal and Coriolis forces, Motion under a central force, Kepler’s laws, Gravitational Law and field, Conservative and non-conservative forces. System of particles, Center of mass, equation of motion of the CM, conservation of linear and angular momentum, conservation of energy, variable mass systems. Elastic and inelastic collisions. Rigid body motion, fixed axis rotations, rotation and translation, moments of Inertia and products of Inertia, parallel and perpendicular axes theorem. Principal moments and axes. Kinematics of moving fluids, equation of continuity, Euler’s equation, Bernoulli’s theorem.
Oscillations, Waves and Optics: Differential equation for simple harmonic oscillator and its general solution. Superposition of two or more simple harmonic oscillators. Lissajous figures. Damped and forced oscillators, resonance. Wave equation, traveling and standing waves in one-dimension. Energy density and energy transmission in waves. Group velocity and phase velocity. Sound waves in media. Doppler Effect. Fermat’s Principle. General theory of image formation. Thick lens, thin lens and lens combinations. Interference of light, optical path retardation. Fraunhofer diffraction. Rayleigh criterion and resolving power. Diffraction gratings. Polarization: linear, circular and elliptic polarization. Double refraction and optical rotation.
Coulomb’s law, Gauss’s law. Electric field and potential. Electrostatic boundary conditions, Solution of Laplace’s equation for simple cases. Conductors, capacitors, dielectrics, dielectric polarization, volume and surface charges, electrostatic energy. Biot-Savart law, Ampere’s law, Faraday’s law of electromagnetic induction, Self and mutual inductance. Alternating currents. Simple DC and AC circuits with R, L and C components. Displacement current, Maxwelll’s equations and plane electromagnetic waves, Poynting’s theorem, reflection and refraction at a dielectric interface, transmission and reflection coefficients (normal incidence only). Lorentz Force and motion of charged particles in electric and magnetic fields.
Elements of Kinetic theory of gases. Velocity distribution and Equipartition of energy. Specific heat of Mono-, di- and tri-atomic gases. Ideal gas, van-der-Waals gas and equation of state. Mean free path. Laws of thermodynamics. Zeroth law and concept of thermal equilibrium. First law and its consequences. Isothermal and adiabatic processes. Reversible, irreversible and quasi-static processes. Second law and entropy. Carnot cycle. Maxwell’s thermodynamic relations and simple applications. Thermodynamic potentials and their applications. Phase transitions and Clausius-Clapeyron equation. Ideas of ensembles, Maxwell-Boltzmann, Fermi-Dirac and Bose-Einstein distributions.
Inertial frames and Galilean invariance. Postulates of special relativity. Lorentz transformations. Length contraction, time dilation. Relativistic velocity addition theorem, mass energy equivalence. Blackbody radiation, photoelectric effect, Compton effect, Bohr’s atomic model, X-rays. Wave-particle duality, Uncertainty principle, the superposition principle, calculation of expectation values, Schrodinger equation and its solution for one, two and three dimensional boxes. Solution of Schrodinger equation for the one dimensional harmonic oscillator. Reflection and transmission at a step potential, Pauli exclusion principle. Structure of atomic nucleus, mass and binding energy. Radioactivity and its applications. Laws of radioactive decay.
Crystal structure, Bravais lattices and basis. Miller indices. X-ray diffraction and Bragg’s law; Intrinsic and extrinsic semiconductors, variation of resistivity with temperature. Fermi level. p-n junction diode, I-V characteristics, Zener diode and its applications, BJT: characteristics in CB, CE, CC modes. Single stage amplifier, two stage R-C coupled amplifiers. Simple Oscillators: Barkhausen condition, sinusoidal oscillators. OPAMP and applications: Inverting and non-inverting amplifier. Boolean algebra: Binary number systems; conversion from one system to another system; binary addition and subtraction. Logic Gates AND, OR, NOT, NAND, NOR exclusive OR; Truth tables; combination of gates; de Morgan’s theorem.